Monday, May 19, 2008

What Other Drugs Will Affect Aminophylline ?
Aminophylline interacts with many other drugs. The following drugs may increase the levels of aminophylline in your blood, leading to dangerous side effects:
  1. Alcohol
  2. Cimetidine (Tagamet, Tagamet HB)
  3. Fluoroquinolone antibiotics such as enoxacin (Penetrex), lomefloxacin (Maxaquin) ciprofloxacin (Cipro), norfloxacin (Noroxin), and ofloxacin (Floxin)
  4. Clarithromycin (Biaxin) and erythromycin (Ery-Tab, E.E.S., E-Mycin, others)
  5. Disulfiram (Antabuse)
  6. Estrogens (Ogen, Premarin, and many other types)
  7. Fluvoxamine (Luvox)
  8. Methotrexate (Folex, Rheumatrex)
  9. Mexiletine (Mexitil) and propafenone (Rythmol)
  10. Propranolol (Inderal)
  11. Tacrine (Cognex)
  12. Ticlopidine (Ticlid)
  13. Verapamil (Verelan, Calan, Isoptin)
The following drugs may decrease aminophylline levels in your blood, leading to poor asthma control:
  1. Aminoglutethimide (Cytadren)
  2. Carbamazepine (Tegretol)
  3. Isoproterenol (Isuprel)
  4. Moricizine (Ethmozine)
  5. Phenobarbital (Luminal, Solfoton)
  6. Phenytoin (Dilantin)
  7. Rifampin (Rifadin)
  8. Sucralfate (Carafate)
How Aminophylline is Supplied ?
  1. Aminophylline is available in 100 mg and 200 mg immediate-release tablets, and as a 105 mg/5 ml oral liquid.
  2. Injectable aminophylline is available in a 250 mg/10 ml concentration.
  3. In addition, aminophylline is also available as 250 mg and 500 mg suppositories.
Who Should Not Take Aminophylline?
  1. Any collection Fluid in your lungs
  2. A thyroid condition
  3. Liver disease
  4. Kidney disease
  5. A stomach ulcer
  6. Seizures or epilepsy
  7. High blood pressure, a heart condition, or any type of heart disease
You may not be able to take aminophylline, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.
  1. If you are over 60 years of age, you may be more likely to experience side effects from aminophylline. You may require a lower dose of this medication.
  2. Aminophylline passes into breast milk and could affect a nursing baby. Do not take aminophylline
  3. Aminophylline is in the FDA pregnancy category C. This means that it is not known whether aminophylline will harm an unborn baby

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